Armenian Diaspora in America is the second largest Armenian community after Armenian Diaspora in Russia. Most of immigrants came to USA in early twentieth century, during and after Armenian genocide in 1915. Second wave arrived to America in 1940s. Also big number of immigrants arrive to USA after Spitac earthquake and then during and after the Nagorno-Karabakh War. The Armenian American community is the most politically influential community of the Armenian diaspora. Organizations such as Armenian National Committee of America and Armenian Assembly of America advocate for the recognition of the Armenian Genocide by the US government and support stronger Armenia–United States relations.

Most Armenian Americans are concentrated in major urban areas, especially in California and the Northeast, and to a lesser extent in the Midwest. The highest concentrations of Americans of Armenian ancestry are in Los Angeles, New York and Boston.

Armenian Americans are one of the least assimilated White ethnic groups in the US. Today, more than half of the Armenians living in the US speak the Armenian language. The main reason of it is that most Armenians in America are foreign-born or first generation of Americans. Also there are enough Armenian-language schools. Most Armenian Americans are adherents of the Armenian Apostolic Church. The first Armenian Apostolic church in America named Church of Our Savior was built in 1891 in Worcester. The first Armenian-language newspaper in the US, named Aregak was published in Jersey City in 1888. Today, numerous Armenian newspapers (both in Armenian and English) are published throughout the country. Asbarez is the only daily, published in Los Angeles since 1908. Four Armenian television stations are located in the Southern California, which has high concentration of Armenian speakers. There are bilingual radio stations that go on air either on Saturdays or Sundays for couple hours in Boston, New Jersey, Providence, Fresno Detroit. Armenian Diaspora is also culturally well organized. A lot of singers, actors gave concerts for American community of Armenians.